Deborah A Howatt Selected Research

Aortic Rupture

1/2022	Fludrocortisone Induces Aortic Pathologies in Mice.
1/2013	Amlodipine reduces AngII-induced aortic aneurysms and atherosclerosis in hypercholesterolemic mice.
1/2012	Doxycycline does not influence established abdominal aortic aneurysms in angiotensin II-infused mice.
1/2009	Interferon-gamma and the interferon-inducible chemokine CXCL10 protect against aneurysm formation and rupture.
8/2006	Rapid dilation of the abdominal aorta during infusion of angiotensin II detected by noninvasive high-frequency ultrasonography.

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Deborah A Howatt Research Topics

Disease

25	Abdominal Aortic Aneurysm 01/2021 - 02/2005
25	Atherosclerosis 01/2021 - 02/2005
9	Hypercholesterolemia 01/2022 - 08/2010
7	Aortic Aneurysm (Aneurysm, Aortic) 01/2022 - 01/2012
7	Aneurysm (Aneurysms) 01/2020 - 08/2006
5	Aortic Rupture 01/2022 - 08/2006
5	Rupture 01/2015 - 08/2006
4	Body Weight (Weight, Body) 10/2020 - 02/2005
4	Inflammation (Inflammations) 10/2017 - 01/2012
4	Ascending Aorta Aneurysm 01/2015 - 03/2010
3	Thoracic Aortic Aneurysm 10/2021 - 01/2013
2	Hemorrhage 01/2022 - 06/2006
2	Atherosclerotic Plaque (Atheroma) 10/2020 - 01/2009
2	Dyslipidemias (Dyslipidemia) 01/2020 - 08/2015
2	Obesity 10/2017 - 05/2015
2	Sepsis (Septicemia) 05/2014 - 06/2013
1	Hypertension (High Blood Pressure) 01/2022
1	Fibrosis (Cirrhosis) 10/2017
1	Virus Diseases (Viral Diseases) 02/2016
1	Fatty Liver 02/2016
1	Infections 01/2016
1	Hyperplasia 09/2015
1	Cardiovascular Diseases (Cardiovascular Disease) 02/2014
1	Hypertrophy 01/2013
1	Hypotension (Low Blood Pressure) 01/2013
1	MYD88 Deficiency 12/2011
1	Thrombosis (Thrombus) 09/2011

Drug/Important Bio-Agent (IBA)

29	Angiotensin IIIBA 01/2021 - 02/2005
16	LDL Receptors (LDL Receptor)IBA 01/2022 - 03/2011
12	Apolipoproteins E (ApoE)IBA 01/2020 - 06/2006
5	CholesterolIBA 10/2020 - 02/2005
4	CalpainIBA 10/2017 - 01/2012
4	ApolipoproteinsIBA 05/2017 - 01/2009
3	AngiotensinsIBA 01/2020 - 08/2015
3	calpastatinIBA 10/2017 - 01/2012
3	Matrix Metalloproteinases (MMPs)IBA 05/2017 - 01/2012
3	Phenobarbital (Luminal)FDA Link 09/2011 - 08/2006
2	Angiotensin IIBA 01/2020 - 02/2016
2	AngiotensinogenIBA 01/2020 - 01/2019
2	ReninIBA 01/2020 - 01/2019
2	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2020 - 01/2016
2	Antisense OligonucleotidesIBA 02/2016 - 01/2016
2	Proteins (Proteins, Gene)FDA Link 01/2016 - 02/2012
2	Lipoproteins (Lipoprotein)IBA 08/2015 - 09/2012
2	Serum Amyloid A Protein (Serum Amyloid A)IBA 05/2015 - 02/2014
2	Angiotensin-Converting Enzyme 2IBA 12/2014 - 04/2011
2	HDL LipoproteinsIBA 05/2014 - 06/2013
2	CytokinesIBA 06/2013 - 01/2009
2	N- 1- (hydroxy(3- oxo- 2- phenyl- 1- cyclopropen- 1- yl)methyl)- 2- methylpropyl- 2- benzenesulfonylamino- 4- methylpentanamideIBA 01/2013 - 01/2012
2	SmokeIBA 09/2012 - 06/2010
1	FludrocortisoneIBA 01/2022
1	Transforming Growth Factor-beta Type II ReceptorIBA 01/2022
1	Angiotensin Receptors (Angiotensin II Receptor)IBA 10/2021
1	Fibrillin-1IBA 10/2021
1	LigandsIBA 10/2021
1	Angiotensin Receptor AntagonistsIBA 10/2021
1	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 11/2020
1	Amino Acids FDA Link 01/2020
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2020
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2020
1	Low Density Lipoprotein Receptor-Related Protein-2IBA 01/2019
1	RelaxinIBA 05/2017
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 05/2017
1	aliskiren FDA Link 02/2016
1	Renin InhibitorsIBA 02/2016
1	Proprotein Convertase 9IBA 01/2016
1	Apolipoproteins B (ApoB)IBA 08/2015
1	Acute-Phase Proteins (Acute-Phase Protein)IBA 05/2015
1	Glucose (Dextrose)FDA LinkGeneric 05/2015
1	AdiponectinIBA 05/2015
1	LipidsIBA 05/2015
1	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 05/2015
1	Low Density Lipoprotein Receptor-Related Protein-1 (LDL-Receptor Related Protein)IBA 01/2015
1	Scavenger Receptors (Scavenger Receptor)IBA 05/2014
1	GlucocorticoidsIBA 05/2014
1	Apolipoprotein A-I (Apolipoprotein A1)IBA 06/2013
1	CorticosteroneIBA 06/2013
1	PD 123319IBA 01/2013
1	Amlodipine (Norvasc)FDA LinkGeneric 01/2013
1	Dietary SodiumIBA 01/2013
1	Protein Isoforms (Isoforms)IBA 01/2013
1	CalciumIBA 01/2012
1	Doxycycline (Periostat)FDA LinkGeneric 01/2012
1	Messenger RNA (mRNA)IBA 01/2012
1	Cysteine Proteases (Cysteine Protease)IBA 01/2012
1	Myeloid Differentiation Factor 88IBA 12/2011
1	Toll-Like Receptors (Toll-Like Receptor)IBA 12/2011
1	Peptides (Polypeptides)IBA 04/2011
1	Telomerase (Telomerase Reverse Transcriptase)IBA 02/2011
1	Group X Phospholipases A2IBA 01/2011
1	Orphan Nuclear ReceptorsIBA 08/2010
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 08/2010
1	coenzyme Q10 (CoQ10)IBA 06/2010
1	Hydralazine (Apresoline)FDA LinkGeneric 05/2009
1	InterferonsIBA 01/2009
1	Transforming Growth Factor beta1 (TGF beta 1)IBA 01/2009

Therapy/Procedure

2	Punctures 05/2014 - 06/2013
2	Ligation 05/2014 - 06/2013
1	Therapeutics 01/2020
1	Subcutaneous Infusions 09/2015